Search results for "SOLUBLE FAS"

showing 2 items of 2 documents

MMP-7 promoter polymorphisms do not influence CD4+ recovery and changes in plasma viral load during antiretroviral therapy for HIV-1 infection.

2005

Summary Matrix metalloproteinase-7 (MMP-7) generates soluble Fas Ligand (FasL), which is involved in the apoptotic loss of CD4+ T cells during HIV infection. We evaluated whether two polymorphisms in MMP-7 promoter could influence CD4+ recover in response to antiretroviral therapy, and found that these polymorphisms are ineffective.

AdultCD4-Positive T-LymphocytesMaleImmunologyHuman immunodeficiency virus (HIV)HIV InfectionsMatrix metalloproteinasemedicine.disease_causeMMP-7; Fas ligand; CD4T cells; HIV infectionFas ligandPlasma viral loadGeneticsHumansMedicineMolecular BiologyGenetics (clinical)Polymorphism Geneticbusiness.industryMetalloendopeptidasesGeneral MedicineMiddle AgedViral LoadAntiretroviral therapySoluble fas ligandCD4 Lymphocyte CountAnti-Retroviral AgentsApoptosisMatrix Metalloproteinase 7ImmunologyHIV-1business
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Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocar…

2014

[Background] The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related to obesity, its association with other cardiovascular risk factors and disease remains uncertain.

MalealelosEndocrinology Diabetes and MetabolismhumanosLOCIMyocardial Infarctionproteínas reguladoras de la apoptosisApoptosisType 2 diabetesVARIANTSDiet Mediterraneanestudios de seguimientoCoronary artery diseaseClinical trialsRisk FactorsMyocardial infarctionLongitudinal Studiesmediana edadOriginal Investigationeducation.field_of_studyancianoDiabetisdietaHàbits alimentarisCAUSE MORTALITYDiabetesSOLUBLE FASMiddle Agedestudios de asociación genéticaMEDITERRANEAN DIETCARDIOVASCULAR-DISEASECORONARY-ARTERY-DISEASEObesitatFemaleCardiology and Cardiovascular Medicinemedicine.medical_specialtyFood habitsPopulationHeart rateproteínas de membranasMediterranean cookingDiabetes mellitusInternal medicineCuina mediterràniamedicineDiabetes MellitusHumansfactores de riesgoJAPANESE POPULATIONGenetic Predisposition to DiseaseObesityGENOME-WIDE ASSOCIATIONeducationobesidadAllelesGenetic Association Studiesinfarto de miocardioAgedPolymorphism Geneticbusiness.industryMembrane Proteinspredisposición genética a la enfermedadmedicine.diseaseObesityFAIM2DietBODY-MASS INDEXInfart de miocardiMyocardial infarctionEndocrinologyBlood pressureDiabetes Mellitus Type 2frecuencia cardíacaestudios longitudinalesbusinessApoptosis Regulatory ProteinsBody mass indexFollow-Up StudiesAssaigs clínics
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